Persistent Pain
Unexplained pain lasting weeks (bone, back, abdominal, headache) may signal various cancers
If pain is new, worsening, or doesn't respond to usual remedies
Skin, Mouth & Visible Changes
#
Symptom
What It Might Signal
When to Seek Care
6
Changes in Skin Appearance
New moles, changing moles (ABCDEs), non-healing sores, yellowing (jaundice)
Any mole changing in size, shape, color; sores not healing in 2–3 weeks
7
Persistent Cough or Hoarseness
Cough >3 weeks, coughing blood, voice changes >2 weeks; may signal lung, throat cancers
If cough persists >3 weeks, especially with smoking history or other risk factors
8
Difficulty Swallowing
Feeling of food "sticking"; may indicate esophageal, throat, or stomach cancers
If swallowing difficulty is new, progressive, or accompanied by weight loss
9
Mouth Changes
White/red patches, sores that don't heal, numbness; may signal oral cancers
If mouth changes last >2 weeks without clear cause (trauma, infection)
10
Unusual Bleeding or Discharge
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